Lab uses the Catalogue of Somatic Mutations in Cancer (COSMIC) to build a database to efficiently identify the HLA-I immunopeptidome

Human leukocyte antigen class I molecules (HLA-I) present intracellular immunopeptides to T cells and provide an ideal source for identifying neoantigens, which have emerged as a promising area of focus in tumor immunotherapy. In this case study, learn how a lab used COSMIC to construct a database for efficient and accurate neoantigen identification.

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