QIAseq Multimodal: Explore the power of one

New! QIAseq Pan-cancer Multimodal Panel for comprehensive genomic profiling of solid tumors and heme malignancies

Unlock insights into multiple cancers with just 10 ng total nucleic acid input

Experience our innovative, single-day sample to sequencing workflow for simultaneous enrichment and profiling of 605 relevant DNA variant and RNA fusion biomarkers found across multiple cancers, as well as assessment of tumor mutational burden (TMB) and microsatellite instability (MSI), from a single sample input of 10 ng.

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high-confidence
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coverage
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time and costs
  • Detect rare variants
  • Reduce index hopping and read mis-assignment
  • Find known and novel fusions
  • Cover GC-rich regions
  • Superior customization
  • Multiple insights from a single extraction and workflow
  • Reduce turnaround time and costs by 50%

Explore the 605 loci, 1.44 Mb panel

Targets genes and RNA fusions implicated in the pathogenesis of solid and heme malignancies

  • Gene targets: Covers exonic regions + 5–10 bases of exon/intron junctions
  • RNA fusions: Targets transcripts in COSMIC, covers exons in both 3’ and 5’ directions
  • Includes full coverage of TERT promoter

Assess key immunotherapy biomarkers:

  • TMB: Coverage of >1 Mb enables statistically significant assessment of tumor mutation load
  • MSI status: 26 loci with well-established utility for correlation to treatment response

Explore this unique, one-day workflow

Enables detection of

  • DNA variants: SNVs, Indels, CNVs
  • RNA: fusions, gene expression, exon skipping events
  • Biomarkers: TMB, MSI

Starting material

  • DNA: 10–40 ng
  • RNA: 10–250 ng
  • Total nucleic acid: 10–40 ng

Sample types

  • FFPE samples, whole blood, cells and tissues

Unique molecular indices (UMIs) and Unique dual indices (UDIs) included

  • Confidently detect low-frequency variants by incorporating UMIs
  • Reduce index hopping and read mis-assignment with UDIs

Experience our oncology solutions

Other QIAseq Multimodal Panels

  • QIAseq Lung Multimodal Panel
  • QIAseq Leukemia Multimodal Panel
  • QIAseq Sarcoma Multimodal Panel

Nucleic acid isolation

  • AllPrep Kits
  • QIAamp DNA and QIAamp RNA Kits

Bioinformatics

  • Pre-optimized secondary analysis with QIAGEN CLC Genomics Workbench
  • Pre-configured variant interpretation with QIAGEN Clinical Insights for QIAseq

Watch the webinars

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Interested in the QIAseq Pan-cancer Multimodal Panel or any of our oncology solutions?
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