On June 1st, the American Academy of Pediatrics released the new Red Book® 2018 edition, which expands established AAP recommendations for TB blood testing in children. The AAP now preferentially recommends the use of TB blood tests (IGRAs) in BCG-vaccinated children aged 2 years and older. The new recommendation updates the AAP's previous recommendation for IGRA testing in children starting at age 5. The updated Red Book guidance was driven by data indicating that BCG-vaccinated children testing positive on TST are overtreated for TB infection. More broadly, the AAP states that among immunocompetent children age 2 or older an IGRA may be used in any situation where a TST would historically be used.
Watch our recorded webinar event to learn more about the new AAP guidelines. During this program, you’ll learn more about the rationale behind the new pediatric IGRA recommendations and LTBI treatment regimens, while looking more broadly at how TB elimination efforts are increasingly focused on employing preventive methods in the primary care setting. The program will be led by Dr. Sonia Qasba, a physician at Suburban Hospital, part of Johns Hopkins Medicine. Dr. Qasba is board certified in Infectious Disease, Internal Medicine, and Pediatrics.
1. WHO. Latent tuberculosis infection: Updated and consolidated guidelines for programmatic management. WHO/CDS/TB/2018.4
QuantiFERON-TB Gold Plus (QFT-Plus) is an in vitro diagnostic aid for detection of Mycobacterium tuberculosis infection. QFT-Plus is an indirect test for M. tuberculosis infection (including disease) and is intended for use in conjunction with risk assessment, radiography, and other medical and diagnostic evaluations. QFT-Plus Package Inserts as well as up-to- date licensing information and product-specific disclaimers can be found at www.QuantiFERON.com.
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